Publications

2020

Brook B, Harbeson DJ, Shannon CP, Cai B, He D, Ben-Othman R, Francis F, Huang J, Varankovich N, Liu A, Bao W, Bjerregaard-AndersenM, Schaltz-Buchholzer F, Sanca L, Golding CN, Lindberg Larsen K, Levy O, Kampmann B, The EPIC Consortium, Tan R, Charles A, Wynn JL, Shann F, Aaby P, Benn CS, Tebbutt SJ, Kollmann TR, Amenyogbe N. BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis. Sci Transl Med 12, eaax4517 DOI: 10.1126/scitranslmed.aax4517

Idoko OT, Smolen KK, Oghenebrume W, Abdulazeez I, Shannon CP, Dibassey T, Direy-Arce J, Darbor A, Strandmark J, Ben-Otham R, Odumade OA, McEnaney K, Amenyogbe N, Pomat WS, van Haren S, Sanchez-Schmitz G, Brinkman R, Steen H, Hancock REW, Tebbutt SJ, Richmond PC, van den Biggelaar AHJ, Kollmann TR, Levy O, Ozonoff A, Kampmann, B. Clinical Protocol for Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea. Front. Pediatr., 30 April 2020 https://doi.org/10.3389/fped.2020.00197

Zhou Q, Wei X-S, Xiang X, Wang Z, Chen V, Shannon CP, Tebbutt SJ, Kollmann TR, Fish EN. Interferon-a2b treatment for COVID-19. medRxiv; doi: https:/doi.org/10.1101/2020.04.06.20042580

2019

Shannon CP, Hollander Z, Dai DLY, Chen V, Assadian S, Lam KK, McManus JE, Zarzycki M, Kim Y, Kim J-YV, Balshaw R, Gidlof O, Ohman J, Smith JG, Toma M, Ignaszewski A, Davies RA, Delgado D, Haddad H, Isaac D, Kim D, Mui A, Rajda M, West L, White M, Zieroth S, Tebbutt SJ, Keown PA, McMaster WR, Ng RT, McManus BM. HEARTBiT: A Transcriptomic Signature for Excluding Acute Cellular Rejection in Adult Heart Allograft Patients. Canadian Journal of Cardiology 2019. In Press. doi:10.1016/j.cjca.2019.11.017.

He D, Xi Yang C, Sahin B, Singh A, Shannon CP, Oliveria JP, Gauvreau GM, Tebbutt SJ. Whole blood vs PBMC: compartmental differences in gene expression profiling exemplified in asthma. Allergy Asthma Clin Immunol 2019; doi: 10.1186/s13223-019-0382-x.

Rajasekaran A, He D, Yue A, Singh A, Shannon CP, Fitzgerald J.M, Boulet L-P, O’Byrne PM, Gauvreau GM, Tebbutt SJ.  Cholinergic synapse pathway gene polymorphisms may play a rold in regulating a type of asthmatic airway response triggered upon allergen challenge. ERJ Open Res 2019; 5:00107-2019. doi: 10.1183/23120541.00107-2019.

Kim JV, Ng RT, Balshaw R, Keown P, McMaster R, McManus B, Lam K, Tebbutt SJ. Clinical Validation and Biomarker Translation. In: Rahbari R, Van Niewaal J, Bleavins MR. Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy, Second Edition. In Press, Wiley, United States; Dec 2019.

Assadian S, Burgess M, Crouch B, Lam K, McManus B. Ethics of Biomarkers: The Borders of Investigative Research, Informed Consent, and Patient Protection. In: Rahbari R, Van Niewaal J, Bleavins MR. Biomarkers in Drug Discovery and Development: A Handbook of Practice, Application, and Strategy, Second Edition. In Press, Wiley, United States; Dec 2019

Takiguchi H, Chen V, Obeidat M, Hollander Z, FitzGerald JM, McManus BM, Ng RT, Sin DD. Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial. Respir Res. 2019 Aug 5;20(1):176. doi: 10.1186/s12931-019-1147-2.

Singh A, He M, Chen V, Hollander Z, Tebbutt SJ, Ng RT, McManus BM, Sin DD, Ratjen F, Quon BS. Blood biomarkers to predict short-term pulmonary exacerbation risk in children and adolescents with CF: A pilot study.J Cyst Fibros. 2019 Jun 5. pii: S1569-1993(19)30774-X. doi: 10.1016/j.jcf.2019.05.020. 

Lam K, Zacour M, Kim JY, Hollander Z, Wideman R, Ng R, Tebbutt SJ, McManus BM. Delivering the personalized medicine promise: best practice recommendations for designing biomarker development processes. Handbook of Biomarkers and Precision Medicine 1st Edition CRC Press. 2019 May 3.

Singh A, Shannon CP, Lê Cao K, Tebbutt SJ. Can Big Data Analytics Recapitulate Biology? A Survey of Multi-omics Data Integration Approaches Handbook of Biomarkers and Precision Medicine 1st Edition CRC Press. 2019 May 3.

Alotaibi NM, Chen V, Hollander Z, Leipsic JA, Hague CJ, Murphy DT, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD. Phenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples. Int J Chron Obstruct Pulmon Dis. 2019 Jan 23;14:311-319. doi: 10.2147/COPD.S188186. eCollection 2019.

Pesenacker AM, Chen V, Gillies J, Speake C, Marwaha AK, Sun A, Chow S, Tan R, Elliott T, Dutz JP, Tebbutt SJ, Levings MK. Treg gene signatures predict and measure type 1 diabetes trajectory. JCI Insight. March 21, 2019. doi.org/10.1172/jci.insight.123879

Lee AH, Shannon CP, Amenyogbe N, Bennike TB, Diray-Arce J, Idoko OT, Gill EE, Ben-Othman R, Pomat WS, van Haren SD, Cao K-A L, Cox M, Darboe A, Falsafi R, Ferrari D, Harbeson DJ, He D, Bing C, Hinshaw SJ, Ndure J, Njie-Jobe J, Pettengill MA, Richmond PC, Ford R, Saleu G, Masiria G, Matlam JP, Kirarock W, Roberts E, Malek M, Sanchez-Schmitz G, Singh A, Angelidou A, Smolen KK, Brinkman RR, Ozonoff A, Hancock REW, van den Biggerlaar AHJ, Steen H, Tebbutt SJ, Kampmann B, Levy O, Kollman TR. Dynamic molecular changes during the first week of human life follow a robust developmental trajectory. Nature Communications. March 2019. DOI: 10.1092

Tigchelaar S., Gupta R, Shannon CP, Streijger F, Sinha S, Flibotte S, Rizzuto M, Street J, Paquette S.J, Ailon T, Charest-Morin R, Dea N, Fisher CG, Dvorak MF, Dhall SS, Mac-Thoing JM, Parent S, Bailey C, Christie S, van Keuren-Jensen K, Nislow C, Kwon BK. MicroRNA biomarkers in cerebrospinal fluid and serum reflect injury severity in human acute traumatic spinal cord injury. J of Neurotrauma. March 2019. DOI:10.1089/neu.2018.6256

Singh A, Shannon CP, Gautier B, Rohart F, Vacher M, Tebbutt SJ, Le Cao K-A. DIABLO: an integrative approach for identifying key molecular drivers from multi-omic assays. Bioinformatics. In press 2019 January 18. https://doi-org.ezproxy.library.ubc.ca/10.1093/bioinformatics/bty1054

Singh A, Dai DLY, Ioannou K, Chen V, Lam KK, Hollander Z, Wilson-McManus JE, Assadian S, Toma M, Ng R, Virani S, Ignaszewski A, Tebbutt S, Bennett M, McManus BM. Ensembling Electrical and Proteogenomics Biomarkers for Improved Prediction of Cardiac-related 3-month Hospitalizations: A Pilot Study. Can J Cardiol. In press 2019 January 4. DOI: 10.1016/j.cjca.2018.12.039

2018

Singh A, Shannon CP, Kim YW, Yang CX, Balshaw R, Cohen Freue GV, Gauvreau GM, Fitzgerald JM, Boulet L, O’Byrne PM, Tebbutt SJ. Novel Blood-based Transcriptional Biomarker Panels Predict the Late-Phase Asthmatic Response. Am J Respir Crit Care Med Vol 197. DOI: 10.1164/rccm.201701-0110OC

Shannon CP, Yang CX, Tebbutt SJ. A Bloody Primer: Analysis of RNA-Seq from Tissue Admixtures. Springer Science + Business Media, LLC 2018. DOI: 10.1007/978-1-4939-7514-3_12

Penn AM, Saly V, Trivedi A, Lesperance ML, Votova K, Jackson AM, Croteau NS, Balshaw RF, Bibok MB, Smith DS, Lam KK, Morrison J, Lu L, Coutts SB, Borchers CH.Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project.Transl Stroke Res2018;1–10. DOI:10.1007/s12975-018-0609-z

Alotaibi NM, Chen V, Hollander Z, Hague CJ, Murphy DT, Leipsic JA, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD. Phenotyping COPD exacerbations using imaging and blood-based biomarkers. International Journal of Chronic Obstructive Pulmonary Disease. 2018 January 8. DOI: 10.2147/COPD.S152484

2017

Sukma Dewi I, Gidlöf O, Hollander Z, Lam KK, Benson MD, Braun OO, Nilsson J, Tebbutt SJ, Ng RT, Öhman J, McManus BM, Smith JG. Immunological Serum Protein Profiles for Noninvasive Detection of Acute Cellular Rejection After Heart Transplantation. J Am Coll Cardiol. 2017 Dec 12;70(23):2946-2947. DOI: 10.1016/j.jacc.2017.10.012.

Streijger F, Skinnider MA, Rogalski JC, Balshaw R, Shannon CP, Prudova A, Belanger L, Ritchie L, Tsang A, Christie S, Parent S, Mac-Thiong JM, Bailey C, Urquhart J, Ailon T, Paquette S, Boyd M, Street J, Fisher CG, Dvorak MF, Borchers CH, Foster LJ, Kwon. A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord InjuryJ Neurotrauma. 2017 Jun 15;34(12):2054-2068. doi: 10.1089/neu.2016.4879 

Kepplinger D, Takhar M, Sasaki M, Hollander Z, Smith D, McManus B, McMaster WR, Ng RT, Cohen Freue GV.PGCA: An Algorithm to Link Protein Groups Created from MS/MS Data.PLoS One. 2017 May 31;12(5):e0177569. DOI: 10.1371/journal.pone.0177569

Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD.Integrative Genomics of Emphysema Associated Genes Reveals Potential Disease Biomarkers.Am J Respir Cell Mol Biol. 2017 May 1. DOI: 10.1165/rcmb.2016-0284OC

Obeidat M, Nie Y, Chen V, Shannon CP, Andiappan AK, Lee B, Rotzschke O, Castaldi PJ, Hersh CP, Fishbane N, Ng R, McManus B, Miller BE, Rennard S, Paré PD, Sin DD.Network-Based Analysis Reveals Novel Gene Signatures in Peripheral Blood of Patients with Chronic Obstructive Pulmonary Disease. Respir Res. 2017 Apr 24;18(1):72. DOI: 10.1186/s12931-017-0558-1

Chen RY, Chen V, Hollander Z, Leipsic JA, Hague CJ, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DDC-reactive Protein and N-Terminal Prohormone Brain Natriuretic Peptide as Biomarkers in Acute Exacerbations of COPD Leading to Hospitalizations.PLoS One. 2017 Mar 22;12(3):e0174063. DOI: 10.1371/journal.pone.0174063

Toma M, Mak GJ, Chen VHollander ZShannon CPLam KKYNg RTTebbutt SJWilson-McManus JEIgnaszewski AAnderson TDyck JRBHowlett JEzekowitz JMcManus BMOudit GY. Differentiating heart failure phenotypes using sex-specific transcriptomic and proteomic biomarker panels.ESC Heart Failure. 2017 March. DOI: 10.1002/ehf2.12136

Sharma A, Kirkpatrick G, Skolnik K, Chen V, Hollander Z, Wilcox P, Quon BS.Clinical utility of C-reactive protein to predict treatment response during cystic fibrosis pulmonary exacerbations.PLoS One. 2017 Feb 8;12(2):e0171229. DOI: 10.1371/journal.pone.0171229

Hollander Z, DeMarco ML, Sadatsafavi M, McManus BM, Ng RT, Sin DD.Biomarker Development in COPD: Moving from P-Values to Products to Impact Patient Care.Chest. 2017 Feb 1. 151(2):455-467. DOI: 10.1016/j.chest.2016.09.012

Khakban A, Sin DD, FitzGerald JM, McManus B, Ng R, Hollander Z, Sadatsafavi M.The Projected Epidemic of COPD Hospitalizations Over the Next 15 Years: A Population Based Perspective. Am J Respir Crit Care Med. 2017 Feb 1;195(3):287-291. DOI: 10.1164/rccm.201606-1162PP

Sukma Dewi I, Hollander Z, Lam KK, McManus JW, Tebbutt SJ, Ng RT, Keown PA, McMaster RW, McManus BM, Gidlöf O, Öhman J. Association of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation. PLoS One. 2017 Jan 26;12(1):e0170842. DOI: 10.1371/journal.pone.0170842

Sukma Dewi I, Celik S, Karlsson A, Hollander Z, Lam K, McManus JW, Tebbutt S, Ng R, Keown P, McMaster R, McManus BM, Öhman J, Gidlöf O.Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 expression.Cardiovasc Res. 2017 Jan 10. pii: cvw244. DOI: 10.1093/cvr/cvw244

Shannon CP, Balshaw R, Chen V, Hollander Z, Toma M, McManus BM, Fitzgerald JM, Sin DD, Ng RT, Tebbutt SJ.Enumerateblood – an R package to estimate the cellular composition of whole blood from Affymetrix Gene ST gene expression profiles.BMC Genomics. 2017 Jan 6;18(1):43. DOI: 10.1186/s12864-016-3460-1

2016

Shannon CP, Chen V, Takhar M, Hollander Z, Balshaw R, McManus BM, Tebbutt SJ, Sin DD, Ng RT. SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations.BMC Bioinformatics. 2016 Nov 14;17(1):460.

Zafari Z, Sin DD, Postma D, Lofdahl, CG, Vonk J, Bryan S, Lam S, Tammemagi M, Khakban R, Man SF, Tashkin D, Wise R, Connett J, McManus B, Ng R, Hollander Z, Sadatsafavi M.Individualised Prediction of Lung Function Decline in COPD.CMAJ. 2016 Oct 4;188(14):1004-1011. DOI: 10.1503/cmaj.151483

Obeidat M, Ding X, Fishbane N, Hollander Z, Ng RT, McManus BM, Miller BE, Rennard S, Paré  PD, Sin DD.The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease.Nicotine Tob Res. 2016 Sep;18(9):1903-9. DOI: 10.1093/ntr/ntw129

Singh A, Gautier B, Shannon CP, Vacher M, Rohart F, Tebbutt SJ, Le Cao KA. DIABLO – an integrative, multi-omics, multivariate method for multi-group classification. bioRxiv 067611; DOI: 10.1101/067611 [Preprint]

Leung J, Chen V, Hollander Z, Dai D, Tebbutt S, Aaron SD, Vandemheen KL, Rennard SI, FitzGerald MJ, Woodruff PG, Lazarus SC, Connett JE, Coxson HO, Miller B, Borchers CH, McManus BM, Ng RT, Sin DD.COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry. PLoS One. 2016 Aug 15;11(8):e0161129. DOI: 10.1371/journal.pone.0161129

Meredith AJ, Dai DL, Chen V, Hollander Z, Ng R, Kaan A, Tebbutt S, Ramanathan K, Cheung A, McManus BM.Circulating biomarker responses to medical management vs. mechanical circulatory support in severe inotrope-dependent acute heart failure.ESC Heart Fail. 2016 Jun;3(2):86-96. DOI: 10.1002/ehf2.12076

Tkacova R, Dai DLY, Vonk JM, Leung JM, Himstra PS, Van den Berge M, Kunz L, Hollander Z, Tashkin, D, Wise R, Connett J, NG RT, McManus BM, Man P, Postma DS, Sin DD.Airway Hyperresponsiveness in COPD: A Marker of Asthma-COPD Overlap Syndrome?.J Allergy Clin Immunol. 2016 Dec;138(6):1571-1579.e10. DOI: 10.1016/j.jaci.2016.04.022

2015

Obeidat M, Fishbane N, Nie Y, Chen V, Hollander Z, Tebbutt SJ, et al. (2015)The Effect of Statins on Blood Gene Expression in COPD. PLoS ONE 10(10): e0140022. DOI:10.1371/journal.pone.0140022

Sin DD, Hollander Z, DeMarco ML, McManus BM, Ng RT.Biomarker Development for COPD: From Discovery to Clinical Implementation.Am J Respir Crit Care Med. 2015 July 15. DOI: 10.1164/rccm.201505-0871PP

Khakban A, Sin DD, FitzGerald JM, Ng R, Zafari Z, McManus B, Hollander Z, Marra CA, Sadatsafavi M.10-Year Trends in Direct Costs of COPD: A Population Based Study.Chest. 2015 Jun 4. DOI: 10.1378/chest.15-0721.

Quon B, Dai DLY, Hollander Z, Ng RT, Tebbutt S, Wilcox S, Sin DD.Discovery Of Novel Plasma Protein Biomarkers To Predict Imminent Cystic Fibrosis Pulmonary Exacerbations Using Multiple Reaction Monitoring Mass Spectrometry. Thorax. 2015 Mar 16. DOI: 10.1136/thoraxjnl-2014-206710. [Epub ahead of print]

Tremlett H, Dai DLY, Hollander Z, Kapanen A, Aziz T, Wilson-McManus JE; Tebbutt SJ, Borchers CH, Oger J, Cohen Freue GV.Serum Proteomics in Multiple Sclerosis Disease Progression. J Proteomics. 2015 Apr 6;118:2-11. DOI: 10.1016/j.jprot.2015.02.018

Hollander, Z., Dai, D. L.Y., Putko, B. N., Yogasundaram, H., Wilson-McManus, J. E., Thompson, R. B., Khan, A., West, M. L., McManus, B. M. and Oudit, G. Y. (2015),Gender-specific plasma proteomic biomarkers in patients with Anderson–Fabry disease. European Journal of Heart Failure, 17: 291–300. DOI: 10.1002/ejhf.230

2014

Hollander Z, Lazarova M, Lam KKY, Ignaszewski A, Oudit GY, Dyck J, Schreiner G, Pauwels J, Chen V, Cohen Freue GV, Ng RT, Wilson-McManus J, Balshaw R, Tebbutt S, McMaster R, Keown PA, McManus BM. Proteomic Biomarkers of Recovered Heart Function. Eur J Heart Fail. 2014 May;16(5):551-9

Shannon CP, Balshaw R, Ng RT, Wilson-McManus JE, Keown P, McMaster R, McManus BM, Landsberg D, Isbel NM, Knoll G, Tebbutt SJ. Two-Stage, In Silico Deconvolution of the Lymphocyte Compartment of the Peripheral Whole Blood Transcriptome in the Context of Acute Kidney Allograft Rejection. PLoS ONE. 2014 April; 9(4):e95224

Shin H, Shannon CP, Fishbane N, Ruan J, Zhou M, Balshaw R, Wilson-McManus JE, Ng RT, McManus BM, and Tebbutt SJ. Variation in RNA-Seq transcriptome profiles of peripheral whole blood from healthy individuals with and without globin depletion. PLoS ONE. 2014 March; 9(3):e91041

Shin H, Günther OP, Hollander Z, Wilson-McManus JE, Ng RT, Balshaw RF, Keown PA, McMaster R, McManus BM, Isbel NM, Knoll G, Tebbutt SJ. Longitudinal Analysis of Whole Blood Transcriptomes to Explore Molecular Signatures Associated With Acute Renal Allograft Rejection. Bioinformatics and Biology Insights. 2014 January; 8:17-33

2013

Lin D, Cohen Freue G, Hollander Z, Mancini J, Sasaki M, Mui A, Wilson-McManus J, Ignaszewski A, Imai C, Meredith A, Balshaw R, Ng R.T., Keown P.A., McMaster R, Carere R, Webb G, McManus BM. Plasma protein bio-signature for detection of cardiac allograft vasculopathy. J Heart Lung Transplant. 2013 July; 32(7):723-733

Scherer A, Günther OP,Balshaw R, Hollander Z, Wilson-McManus J, Ng R, McMaster R, McManus BM, Keown P. Alteration of human gene expression profile in uremia. BMC Med Genomics. 2013 Jun 28;6(1):23

Cohen Freue G, Meredith A, Smith D, Bergman A, Sasaki M, Lam K, Hollander Z, Opushneva N, Takhar M, Lin D, Wilson-McManus J, Balshaw R, Keown P, Borchers C, McManus BM, Ng R.T.Computational biomarker pipeline from discovery to clinical implementation; plasma proteomic biomarkers for cardiac transplantation. PLoS Comput biol, 2013 Apr; 9(4):e1002963

Hollander Z, Chen V, Lin D, Ng R.T., Balshaw R, Cohen Freue G, Ignaszewski A, Imai C, Kaan A, Wilson-McManus J, McMaster R, Keown P, McManus BM.Predicting acute cardiac allograft rejection using donor and recipient gene expression. J Heart Lung Transplant. 2013 Feb; 32(2):259-65

2012

Günther OP, Chen V, Cohen Freue G, Balshaw RF, Tebbutt SJ, Hollander Z, Takhar M, McMaster R, McManus BM, Keown PA, Ng R.A computational pipeline for the development of multi marker bio-signature panels and ensemble classifiers. BMC Bioinformatics. 2012 December; 13:326

Shannon C, Hollander Z, Wilson-McManus J, Balshaw RF, Ng RT, McMaster R, McManus BM, Keown P, Tebbutt SJ.White Blood Cell Differentials Enrich Whole Blood Expression Data in the Context of Acute Cardiac Allograft Rejection. Bioinform and Biology Insights. 2012 April; 6:49-61

Tebbutt SJ, He JQ, Singh A, Shannon CP, Ruan J, Carlsten C. Transcriptional Changes of Blood Eosinophils After Methacholine Inhalation Challenge in Asthmatics. Genomics Insights. 2012 Jan 30;5:1-12. DOI: 10.4137/GEI.S9125

2011

Lin D, Hollander Z, Meredith A, Stadnick E, Sasaki M, Cohen Freue G, Qasimi P, Mui A, Ng RT, Balshaw RF, Wilson-McManus JE, Wishart D, Hau D, Keown PA, McMaster R, McManus BM. Molecular signatures of end-stage heart failure. Journal of Cardiac Failure. 2011 October; 17(10):867-874

Gunther OP, Lin d, Balshaw RF, Ng RT, Hollander Z, Wilson-McManus J, McMaster WR, McManus B, Keown PA.Effects of sample timing and treatment on gene expression in early acute renal allograft rejection. Transplantation. 2011 Feb; 91(3):323-329

Psychogios N, Hau D, Peng J, Guo AC, Mandal R, Bouatra S, Sinelnikov I, Krishnamurthy R, Eisner R, Gautam B, Young N, Xia J, Knox C, Dong E, Huang P, Hollander Z, Pedersen T, Bamforth F, Greiner R, McManus B, Newman J, Wishart DS.The human serum metabolome. PLoS ONE. 2011 Feb; 6(2):e16957

2010

Hollander Z, Lin D, Chen V, Ng R, Wilson-McManus J, Ignaszewski A, Cohen Freue G, Balshaw R, Mui A, McMaster R, Keown PA, McManus BM for the NCE CECR PROOF Centre of Excellence.Whole Blood Biomarkers of Acute Cardiac Allograft Rejection: Double-Crossing the Biopsy. Transplantation. 2010 Dec; 90(12):1388-93

Cohen Freue G,V Sasaki M, Meredith A, Günther OP, Bergman A, Takhar M, Mui A, Balshaw RF, Ng RT, Opushneva N, Hollander Z, Guiyun L, Borchers C, Wilson-McManus J, McManus BM, Keown PA, McMaster WR for the Genome Canada Biomarkers in Transplantation Group.Proteomic signatures in plasma during early acute renal allograft rejection. Mol Cell Proteomics. 2010 Sept; 9:1954-1967

2009

Günther O, Balshaw R, Scherer A, Hollander Z, Mui A, Triche T, Cohen Freue G, Li G, Ng R, Wilson-McManus J, McMaster WR, McManus BM, Keown PA for the Biomarkers in Transplantation Team.Functional genomic analysis of peripheral blood during early acute renal allograft rejection. Transplantation. 2009 Oct; 88(7):942-951

Lin D, Hollander Z, Ng RT, Imai C, Ignaszewski A, Balshaw R, Cohen Freue G, Wilson-McManus JE, Qasimi P, Mui A, Triche T, McMaster R, Keown PA, McManus BM for the Biomarkers in Transplantation Team.Whole blood genomic biomarkers of acute heart allograft rejection. The Journal of Heart and Lung Transplantation. 2009 Sept; 28(9): 927-935

Lin D, Hollander Z, Meredith A, McManus B.Searching for “Omic” biomarkers. The Canadian Journal of Cardiology. 2009 Jun; 25(A):9A-14A